BACILLUS SUBTILIS

Bio-Az® Synbiotic

Core Benefits

Survives Stomach Acid

Gut & Immune Health 

Nutrient Absorption

Microbial Regulation

Bacillus subtilis is a breakthrough soil-based, spore-forming probiotic clinically proven to survive where others fail. Unlike fragile strains that degrade during processing or are destroyed by stomach acid, this resilient organism is built to activate exactly where it matters—in the colon, your microbiome’s true command centre. Found in both PureFlow and PureGut, Bacillus subtilis doesn’t just support gut health—it transforms it, optimising nutrient absorption, boosting immune intelligence, and crowding out harmful bacteria with precision and power.

Body of Contents

01. What is it? 02. Benefits 03. Further Research & Studies

What it is

A Living Probiotic Engineered for Results

Bacillus subtilis is a clinically validated spore-forming probiotic that resists heat, light, stomach acid, and long-term storage—unlike traditional strains that often die before reaching the gut. Once inside the body, it travels intact through the digestive tract and activates in the colon, where the majority of your microbiota reside. It supports digestion by producing enzymes that break down proteins, fats, and complex carbs, making nutrients more bioavailable. It also produces essential postbiotic nutrients such as B vitamins and vitamin K2—further enhancing your body’s metabolic and immune functions.

Intelligent by Design: Quorum Sensing Activation 

Bacillus subtilis communicates through quorum sensing—an advanced cellular signalling process that allows bacteria to coordinate their actions in real time. This means it doesn’t just survive, it thinks. By responding to its environment, this intelligent strain adapts to your internal needs, working where and when it’s needed most to support a balanced, resilient gut ecosystem.

Benefits

How Bacillus subtilis Supports Your Gut, Immune System & Whole-Body Health

Clinically Proven Survivability 

Its spore-forming nature allows Bacillus subtilis to resist heat, pressure, acidity, and oxygen—ensuring live delivery to the colon, unlike many probiotics that never make it past the stomach.

Supports Digestive Function 

Produces natural enzymes to break down proteins, fats, and carbs—improving digestion, nutrient absorption, and reducing bloating and discomfort.

Immune Intelligence 

Modulates the immune system and helps the body distinguish between friend and foe—enhancing defense while reducing unnecessary inflammation.

Regulates Gut Microbiota 

Crowds out harmful bacteria and pathogens while enhancing the survival of beneficial microbes—restoring balance to the intestinal environment.

Postbiotic Nutrient Production 

Naturally generates B vitamins (including B2, B7, B9, B12) and K2, which support energy metabolism, blood health, and cellular repair.

Cardiometabolic Support 

Emerging research shows Bacillus subtilis may assist in lowering LDL cholesterol and supporting healthier blood pressure by improving lipid metabolism and reducing systemic inflammation. 

Why It’s in PureFlow & PureGut

Most probiotics die before they make it to your gut. Bacillus subtilis doesn’t. It arrives alive, activates in your colon, and goes to work—enhancing digestion, reducing inflammation, and producing beneficial compounds that support your immune system and long-term health. Its ability to thrive under pressure, communicate intelligently, and work in synergy with other ingredients makes it a cornerstone of both PureFlow and PureGut. 

PURE FLOW

19 reviews

A world’s first daily detoxifier, designed to purify the blood and support immune health. This powerful, pure formula features our PlasmPure Complex—targeting a healthy inflammatory response while supporting natural energy, vitality, and overall well-being.

$150 NZD

PURE GUT

26 reviews

Powered by our Microbiome, Immune & Skin Complex—built to survive stomach acid and activate where it matters most: in the small intestine and colon, where your microbiome thrives.

$90 NZD

Further Research & Studies

Bio-az®

Proven Shelf & Acid Stability

Bio-az® trials show the Bacillus subtilis BA142 strain withstands pasteurisation at 97°C, remains shelf-stable for 24+ months, and survives stomach acid—outperforming most common strains.

Read Study

National Library of Medicine

Colon Germination & Activation in Humans

Clinical evidence confirms B. subtilis spores germinate into active cells in the human small intestine within 3–6 hours of ingestion—highlighting reliable colon activation.

Read Study

National Library of Medicine

Immune Modulation & Anti-Pathogenic Effects

Bacillus subtilis has been shown to suppress harmful pathogens while enhancing immune responsiveness without triggering excessive inflammation.

Read Study

National Library of Medicine

Nutrient Absorption, B Vitamin Synthesis & Gut Integrity

This strain helps improve gut lining integrity, postbiotic production, and absorption of key nutrients, promoting systemic wellness from the inside out.

Read Study

Benefits

SHOP THE PURIFY ME RANGE

PURE FLOW

19 reviews

A world’s first daily detoxifier, designed to purify the blood and support immune health. This powerful, pure formula features our PlasmPure Complex—targeting a healthy inflammatory response while supporting natural energy, vitality, and overall well-being.

$150 NZD

PURE GUT

26 reviews

Powered by our Microbiome, Immune & Skin Complex—built to survive stomach acid and activate where it matters most: in the small intestine and colon, where your microbiome thrives.

$90 NZD

PURE MIND

15 reviews

A first-of-its-kind cognitive detoxifier, designed to help clear brain fog, reduce mental fatigue, and support long-term brain health.

$135 NZD

DAILY ESSENTIALS

22 reviews

Your daily ritual. Elevate your wellness—every single day.

Designed to purify your gut, heart, and mind, this powerful trinity works synergistically to help your body combat toxins, ease inflammation, and restore balance—so you wake up feeling clear, energised, rejuvenated, and thriving.

$329 NZD $375 NZD

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